School of Medicine: Recent submissions

Now showing items 381-400 of 567

    • Safety and immunogenicity of the RTS, S/AS01 malaria vaccine in infants and children identified as HIV-infected during a randomized trial in sub-Saharan Africa 

      Lucas Otieno, Yolanda Guerra Mendoza, Samuel Adjei, Tsiri Agbenyega, Selidji Todagbe Agnandji, Pedro Aide, Pauline Akoo, Daniel Ansong, Kwaku Poku Asante, James A Berkley, Samwel Gesase, Mary J Hamel, Irving Hoffman, Seyram Kaali, Portia Kamthunzi, Simon Kariuki, Peter Kremsner, Miguel Lanaspa, Bertrand Lell, Marc Lievens, John Lusingu, Anangisye Malabeja, Nahya Salim Masoud, Ali Takadir Mtoro, Patricia Njuguna, Opokua Ofori-Anyinam, Godfrey Allan Otieno, Walter Otieno, Seth Owusu-Agyei, Lode Schuerman, Hermann Sorgho, Marcel Tanner, Halidou Tinto, Innocent Valea, Pascale Vandoolaeghe, Jahit Sacarlal, Martina Oneko (Vaccine, 2020)
      We assessed the safety and immunogenicity of the RTS,S/AS01 malaria vaccine in a subset of children identified as HIV-infected during a large phase III randomized controlled trial conducted in seven sub-Saharan African ...

    • Association between Haematological parameters and Sickle cell genotypes in children with Plasmodium falciparum malaria residents in Kisumu County in Western Kenya 

      Paul Kosiyo, Walter Otieno, Jesse Gitaka, Elly O Munde, Collins Ouma (Research Squire, 2020)
      ackground: Sickle cell disease (SCD) is a monogenic disorder due to point mutation in the β-globin gene resulting in substitution of Valine for Glutamic acid. The SCD is prevalent in P. falciparum endemic regions such as ...

    • Estimating Annual Fluctuations in Malaria Transmission Intensity and in the Use of Malaria Control Interventions in Five Sub-Saharan African Countries 

      RTS, S Epidemiology EPI-MAL-005 Study Group, Elisha Adeniji, Kwaku Poku Asante, Owusu Boahen, Guillaume Compaoré, Boubacar Coulibaly, Seyram Kaali, Youssouf Kabore, Mathieu Lamy, John Lusingu, Anangisye Malabeja, Petra Mens, Mattéa Orsini, Lucas Otieno, Walter Otieno, Seth Owusu-Agyei, Janet Oyieko, Jean-Yves Pirçon, Nicolas Praet, François Roman, Ali Sie, Valentine Sing’oei, Sodiomon B Sirima, Khadime Sylla, Roger Tine, Alfred B Tiono, Mathilda Tivura, Effua Usuf, Stéphanie Wéry (The American Society of Tropical Medicine and Hygiene, 2020)
      RTS,S/AS01E malaria vaccine safety, effectiveness, and impact will be assessed in pre- and post-vaccine introduction studies, comparing the occurrence of malaria cases and adverse events in vaccinated versus unvaccinate ...

    • Malignant obstructive jaundice: Factors predictive of non Resectability at kenyatta National Hospital 

      Sandey Ochieng'Bitta Caesar (University of Nairobi, 2010)
      Malignant obstructive jaundice is a rising cause of mortality and morbidity in surgical patients worldwide. Most patients at time of presentation have advanced disease. Surgery remains the only curative mode of treatment ...

    • Sigmoid volvulus in pregnancy 

      WO Kaisha, C Bitta, W Kaisha (The Surgical Society of Kenya, 2010)
      Sigmoid volvulus in pregnancy is a rare condition that poses a myriad of challenges in diagnosis and management of the patient. It demands on the clinician a high index of suspicion, immediate treatment involving resuscitation ...

    • Utility of CT scan and CA 19-9 in Predicting Non Resectability in Malignant Obstructive Jaundice . Feb 2014. :1. 22-27. 

      Kaisha W Bitta C, Githaiga J (2014-02)
      Background: Most patients with malignant obstructive jaundice (MOJ) present with non-resectable disease. Non curative laparotomy has been associated with adverse outcome. There is need to predict non-resectable disease and ...

    • The ASOS Surgical Risk Calculator: development and validation of a tool for identifying African surgical patients at risk of severe postoperative complications 

      H-L Kluyts, Y Le Manach, DM Munlemvo, F Madzimbamuto, A Basenero, Y Coulibaly, S Rakotoarison, V Gobin, AL Samateh, MS Chaibou, AO Omigbodun, SD Amanor-Boadu, J Tumukunde, TE Madiba, RM Pearse, BM Biccard, Hippolyte Abadagan, N Abbas, A Ibrahim Abdelatif, Traoré Abdoulaye, A Abd-rouf, A Abduljalil, A Abdulrahman, S Abdurazig, A Abokris, W Abozaid, SOA Abugassa, F Abuhdema, SA Abujanah, R Abusamra, A Abushnaf, SA Abusnina, TS Abuzalout, HM Ackermann, YB Adamu, A Addanfour, DM Adeleke, TA Adigun, AO Adisa, Sèhivè Valéry Adjignon, NA Adu-Aryee, BB Afolabi, AFX Agaba, PKA Agaba, K Aghadi, H Agilla, B Ahmed, El-Z Ahmed, Al-J Ahmed, M Ahmed, Rene Ahossi, SA Aji, S Akanyun, I Akhideno, M Akhter, OA Akinyemi, M Akkari, Joseph Akodjenou, AL AL Samateh, ES al Shams, OT Alagbe-Briggs, EA Alakkari, RB Alalem, M Alashhab, OI Alatise, A Alatresh, MSI Alayeb Alayeb, BA Albakosh, F Albert, ANJD Alberts, AD Aldarrat, A Alfari, A Alfetore, M Algbali, A Algddar, HA Algedar, IA Alghafoud, A Alghazali, M Alhajj, A Alhendery Alhendery, FFH Alhoty, A Ali, YA Ali, Beye Seïdina Alioune, MA Alkassem, MA Alkchr, TS Alkesa, A Alkilani, F Alkobty Alkobty, Thomas Allaye, SBM Alleesaib, A Alli, K Allopi, NL Allorto, A Almajbery, R Almesmary, SHA Almisslati, F Almoraid, H Alobeidi, MA Alomami, Christella S Alphonsus, OA Alqawi, AA Alraheem, SA Alsabri, A Alsayed, B Alsellabi, M Al-Serksi, MSA Alshareef, AA Altagazi, JS Aluvale, HW Alwahedi, EA Alzahra, MA Alzarouk, K Al-Zubaidy, M Amadou, Maiga Amadou, Simbo D Amanor-Boadu, Al-A Amer, BT Amisi, MA Amuthenu, TWA Anabah, Felix Anani, PGR Anderson, AGB Andriamampionona, L Andrianina, A Anele, R Angelin, N Anjar, O Antùnez, Akwasi Antwi-Kusi, LJC Anyanwu, AA Aribi, OA Arowolo, O Arrey, Daniel Zemenfes Ashebir, SB Assefa, Guy Assoum, V Athanse, JS Athombo, M Atiku, E Atito-Narh, Anatole Atomabe, A Attia, M Aungraheeta, DMA Aurélia, OO Ayandipo, AET Ayebale, HMZ Azzaidey, NB Babajee, HB Badi (Elsevier, 2018-12-01)
      Background The African Surgical Outcomes Study (ASOS) showed that surgical patients in Africa have a mortality twice the global average. Existing risk assessment tools are not valid for use in this population because the ...

    • Maternal and neonatal outcomes after caesarean delivery in the African Surgical Outcomes Study: a 7-day prospective observational cohort study 

      David Bishop, Robert A Dyer, Salome Maswime, Reitze N Rodseth, Dominique van Dyk, Hyla-Louise Kluyts, Janat T Tumukunde, Farai D Madzimbamuto, Abdulaziz M Elkhogia, Andrew KN Ndonga, Zipporah WW Ngumi, Akinyinka O Omigbodun, Simbo D Amanor-Boadu, Eugene Zoumenou, Apollo Basenero, Dolly M Munlemvo, Coulibaly Youssouf, Gabriel Ndayisaba, Akwasi Antwi-Kusi, Veekash Gobin, Patrice Forget, Bernard Mbwele, Henry Ndasi, Sylvia R Rakotoarison, Ahmadou L Samateh, Ryad Mehyaoui, Ushmaben Patel-Mujajati, Chaibou M Sani, Tonya M Esterhuizen, Thandinkosi E Madiba, Rupert M Pearse, Bruce M Biccard, Hippolyte Abadagan, N Abbas, A Ibrahim Abdelatif, Traoré Abdoulaye, A Abd-rouf, A Abduljalil, A Abdulrahman, S Abdurazig, A Abokris, W Abozaid, SOA Abugassa, F Abuhdema, SA Abujanah, R Abusamra, A Abushnaf, SA Abusnina, TS Abuzalout, HM Ackermann, YB Adamu, A Addanfour, DM Adeleke, TA Adigun, AO Adisa, Sèhivè Valéry Adjignon, NA Adu-Aryee, BB Afolabi, AFX Agaba, PKA Agaba, K Aghadi, H Agilla, B Ahmed, El-Z Ahmed, Al-J Ahmed, M Ahmed, Rene Ahossi, SA Aji, S Akanyun, I Akhideno, M Akhter, OA Akinyemi, M Akkari, Joseph Akodjenou, AL AL Samateh, ES al Shams, OT Alagbe-Briggs, EA Alakkari, RB Alalem, M Alashhab, OI Alatise, A Alatresh, MSI Alayeb Alayeb, BA Albakosh, F Albert, ANJD Alberts, AD Aldarrat, A Alfari, A Alfetore, M Algbali, A Algddar, HA Algedar, IA Alghafoud, A Alghazali, M Alhajj, A Alhendery Alhendery, FFH Alhoty, A Ali, YA Ali, Beye Seïdina Alioune, MA Alkassem, MA Alkchr, TS Alkesa, A Alkilani, F Alkobty Alkobty, Thomas Allaye, SBM Alleesaib, A Alli, K Allopi, NL Allorto, A Almajbery, R Almesmary, SHA Almisslati, F Almoraid, H Alobeidi, MA Alomami, Christella S Alphonsus, OA Alqawi, AA Alraheem, SA Alsabri, A Alsayed, B Alsellabi, M Al-Serksi, MSA Alshareef, AA Altagazi, JS Aluvale, HW Alwahedi, EA Alzahra, MA Alzarouk, K Al-Zubaidy, M Amadou, Maiga Amadou, Al-A Amer, BT Amisi, MA Amuthenu, TWA Anabah, Felix Anani, PGR Anderson, AGB Andriamampionona, L Andrianina, A Anele, R Angelin, N Anjar, O Antùnez, LJC Anyanwu, AA Aribi, OA Arowolo, O Arrey, Daniel Zemenfes Ashebir, SB Assefa (Elsevier, 2019-04-01)
      Background Maternal and neonatal mortality is high in Africa, but few large, prospective studies have been done to investigate the risk factors associated with these poor maternal and neonatal outcomes. Methods A 7-day, ...

    • Adult Wilms Tumour in pregnancy 

      Owen Mangusu, Amata Bryan, Oyaya Cyndy, Bitta caesar (AJOL, 2020)
      Wilms’ tumor (nephroblastoma) is the most common primary renal malignancy in children, with a peak presentation in the ages 3-4 years. Wilms’ tumor is extremely rare in adults with around 300 cases described in literature. ...

    • An analysis of pregnancy-related mortality in the KEMRI/CDC health and demographic surveillance system in western Kenya 

      Meghna Desai, Penelope A Phillips-Howard, Frank O Odhiambo, Abraham Katana, Peter Ouma, Mary J Hamel, Jackton Omoto, Sheila Macharia, Annemieke van Eijk, Sheila Ogwang, Laurence Slutsker, Kayla F Laserson (Public Library of Science, 2013-07-16)
      Background Pregnancy-related (PR) deaths are often a result of direct obstetric complications occurring at childbirth. Methods and Findings To estimate the burden of and characterize risk factors for PR mortality, we ...

    • Adolescent schoolgirls' experiences of menstrual cups and pads in rural western Kenya: a qualitative study 

      Linda Mason, KAYLA F LASERSON, Kelvin Oruko, Elizabeth Nyothach, Kelly T Alexander, Frank O Odhiambo, Alie Eleveld, EMILY ISIYE, ISAAC NGERE, JACKTON OMOTO, AISHA MOHAMMED, JOHN VULULE, PENELOPE A PHILLIPS-HOWARD (Practical Action Publishing, 2015-01-01)
      Poor menstrual hygiene management (MHM) among schoolgirls in low-income countries affects girls' dignity, self-esteem, and schooling. Hygienic, effective, and sustainable menstrual products are required. A randomized ...

    • Menstrual cups and sanitary pads to reduce school attrition, and sexually transmitted and reproductive tract infections: a cluster randomised controlled feasibility study in … 

      Penelope A Phillips-Howard, Elizabeth Nyothach, Feiko O ter Kuile, Jackton Omoto, Duolao Wang, Clement Zeh, Clayton Onyango, Linda Mason, Kelly T Alexander, Frank O Odhiambo, Alie Eleveld, Aisha Mohammed, Anna M van Eijk, Rhiannon Tudor Edwards, John Vulule, Brian Faragher, Kayla F Laserson (British Medical Journal Publishing Group, 2016-11-01)
      Objectives Conduct a feasibility study on the effect of menstrual hygiene on schoolgirls9 school and health (reproductive/sexual) outcomes. Design 3-arm single-site open cluster randomised controlled pilot study. Setting 30 ...

    • Examining the safety of menstrual cups among rural primary school girls in western Kenya: observational studies nested in a randomised controlled feasibility study 

      Jane Juma, Elizabeth Nyothach, Kayla F Laserson, Clifford Oduor, Lilian Arita, Caroline Ouma, Kelvin Oruko, Jackton Omoto, Linda Mason, Kelly T Alexander, Barry Fields, Clayton Onyango, Penelope A Phillips-Howard (British Medical Journal Publishing Group, 2017-04-01)
      Objective Examine the safety of menstrual cups against sanitary pads and usual practice in Kenyan schoolgirls. Design Observational studies nested in a cluster randomised controlled feasibility study. Setting 30 primary ...

    • Lay health worker experiences administering a multi-level combination intervention to improve PMTCT retention 

      Abby DiCarlo, Ruby Fayorsey, Masila Syengo, Duncan Chege, Martin Sirengo, William Reidy, Juliana Otieno, Jackton Omoto, Mark P Hawken, Elaine J Abrams (BioMed Central, 2018-12)
      The recent scale-up of prevention of mother-to-child transmission of HIV (PMTCT) services has rapidly accelerated antiretroviral therapy (ART) uptake among pregnant and postpartum women in sub-Saharan Africa. The Mother ...

    • Use of menstrual cups among school girls: longitudinal observations nested in a randomised controlled feasibility study in rural western Kenya 

      Anna Maria van Eijk, Kayla F Laserson, Elizabeth Nyothach, Kelvin Oruko, Jackton Omoto, Linda Mason, Kelly Alexander, Clifford Oduor, Aisha Mohammed, Alie Eleveld, Isaac Ngere, David Obor, John Vulule, Penelope A Phillips-Howard (BioMed Central, 2018-12-01)
      Background A menstrual cup can be a good solution for menstrual hygiene management in economically challenged settings. As part of a pilot study we assessed uptake and maintenance of cup use among young school girls in ...

    • Safety and Acceptability of Thermal Ablation for Treatment of Human Papillomavirus Among Women Living With HIV in Western Kenya 

      Chemtai Mungo, Cirilus Ogollah Osongo, Jeniffer Ambaka, Magdalene A Randa, Jackton Omoto, Craig R Cohen, Megan Huchko (American Society of Clinical Oncology, 2020-07)
      PURPOSE The WHO now recommends thermal ablation as an alternative to cryotherapy within “screen-and-treat” cervical cancer programs in low- and middle-income countries (LMICs). We conducted a safety and acceptability ...

    • Utilization of Herbal Medicines among Diabetic Patients Attending Kenyatta National Hospital Outpatient Clinic 

      Okoth Molly Elsa, Kimani Kuria, David Nyamu, Evans Mwangangi (Journal of Complementary and Alternative Medical Research, 2017-06-15)
      World Health Organization has estimated that 70-90 % of Africa’s population still relies on herbal remedies in order to meet their healthcare needs. Although the role of herbal medicines in the management of diabetes is ...

    • An assessment of facility-based care of diabetes, hypertension, and heart failure across western Kenya 

      P Tulshian, H Zubairi, S Villegas, V Palanivel, BD Nelson, K Ouma, TF Burke (Kenya Medical Association, 2018)
      Low- and middle- income countries account for three-fourths of the global non- communicable disease related mortality. In response to the increasing number of non- communicable disease diagnoses in Kenya, the government ...

    • Wound dressing techniques and costs at a county hospital 

      Pamela Amatta Odhiambo, Kennedy Omondi (The Surgical Society of Kenya, 2019)
      Wound management is one of the commonest procedures conducted in surgical departments across health facilities in Kenya.

    • Hemifacial spasm: case report 

      JO Jowi, J Matende, MI Macharia (Kenya Medical Association, 2006-07)
      A 53 year old lady with diabetes mellitus presented with right hemi-facial spasm (HFS). Brain MRI Scan revealed extensive pan-sinusitis and mild bilateral mastoiditis. She responded well to intravenous ceftriaxone therapy ...