School of Medicine: Recent submissions
Now showing items 521-540 of 567
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Functional characterization and protein–protein interactions of trypanosome splicing factors U2AF35, U2AF65 and SF1
(Elsevier, 2009-04-01)Early in the assembly of the spliceosome of eukaryotes the branch-point binding protein (BBP, also called SF1) recognizes the branch point sequence, whereas the heterodimer U2AF consisting of a 65 and a 35 kDa subunit, ... -
Protein–protein interaction map of the Trypanosoma cruzi ribosomal P protein complex
(Elsevier, 2005-09-12)The large subunit of the eukaryotic ribosome possesses a long and protruding stalk formed by the ribosomal P proteins. Four out of five ribosomal P proteins of Trypanosoma cruzi, TcP0, TcP1α, TcP2α, and TcP2β had been ... -
Molecular characterization of tsetse’s proboscis and its response to Trypanosoma congolense infection
(Public Library of Science, 2017)Tsetse flies (Glossina spp.) transmit parasitic African trypanosomes (Trypanosoma spp.), including Trypanosoma congolense, which causes animal African trypanosomiasis (AAT). AAT detrimentally affects agricultural activities ... -
Defects in resting metabolic rates and mitochondrial respiration in Kwashiorkor and dietary obese rats
(Springer-Verlag, 1991-07-01)Resting metabolic rates have been measured and compared with hepatic mitochondrial respiration in Kwashiorkor and diet-induced obese weaned rats. In Kwashiorkor, resting metabolic rate was 21% lower than the value of ... -
The effect of l-thyroxine on the anaemia response in Trypanosoma congolense infected rabbits
(Elsevier, 1995-06-01)The development of anaemia is a major pathological manifestation in chronic trypanosomosis. The anaemia in African trypanosomosis coincides with a marked decrease in plasma concentration of both thyroxine (T 4) and 3, ... -
Sehistosoma Mansoni in the Baboon: Modulation of Pathology After Vaccination with Polyclonal Anti‐Idiotypic Antibodies
(Blackwell Publishing Ltd, 1995-12-01)Vaccination of five baboons with an anti-idiotypic vaccine to irradiated Schistosoma mansoni cercariae resulted in nearly 19% protection compared to 39% protection conferred to five baboons vaccinated with an irradiated ... -
Perception of Academic Staff in Kenyan Public Universities towards Application of Performance Appraisal Results in Training and Promotion decisions
(2011-11)PERCEPTION OF ACADEMIC STAFF IN KENYAN PUBLIC UNIVERSITIES TOWARDS APPLICATION OF PERFORMANCE APPRAISAL RESULTS IN TRAINING AND PROMOTION DECISIONS DOMINIC WERE MAKAWITI A Management Research Project Submitted in ... -
In vitro interstitial (Leydig) cell response to LH and concentrations of plasma testosterone and LH in the naked mole rat (Heterocephalus glaber, Ruppell)
(Blackwell Publishing Ltd, 1991-03-01)Summary Reproductive endocrinology of the male naked mole rat (Heterocephalus glaber) caught in the wild was studied. In vitro treatment of isolated Leydig cells using either normal dose of LH capable of stimulating ... -
Delayed recovery of adrenocortical and testicular function after chemotherapy of human trypanosomiasis
(Elsevier, 2018)The following indicators of pituitary, adreno-cortical and testicular function were measured in 58 male African trypanosomiasis patients from Western Kenya; plasma cortisol, luteinizing hormone (LH) and testosterone ... -
Thyroid status and adenosine triphosphataseactivity in experimental Trypanosoma congolense infection in rabbits
(Saunders, 1996-11-01)Summary The effect of trypanosome infection on the plasma levels and ratios of tri- iodothyronine (T 3) and thyroxine (T 4) as well as the activity of mitochondrial adenosine triphosphatase (ATPase) were investigated. ... -
Effect of naturally occurring plant quinones on insect flight muscle mitochondrial respiration
(FEDERATION AMER SOC EXP BIOL, 1997-07-31) -
The effect of Trypanosoma vivax infection on late pregnancy and postpartum return to cyclicity in Boran cattle
(Elsevier, 1996-10-01)A study was designed to examine the effect of infection with Trypanosoma vivax KETRI 2501 on the maintenance of pregnancy and postpartum return to reproductive function in susceptible Galana (n= 6) and trypano-tolerant ... -
The pesticide heptachlor affects steroid hormone secretion in isolated follicular and luteal cells of rat
(Elsevier, 2006-09-01)Heptachlor, a chlorinated hydrocarbon pesticide, suppresses the production of progesterone and estradiol in the female rat in vivo or in isolated ovaries in vitro. In this study the effect of heptachlor on steroid ... -
The oxytocic properties of Luffa cylindrica (L.) M. Roem. and Bidens pilosa L., traditionally used medicinal plants from western Uganda
(Blackwell Publishing Ltd, 2007-12-01)The usage of medicinal plants in childbirth in Uganda is a long standing tradition. Over 80% of Ugandan women have childbirth at home and herbal remedies are administered to complete the process of childbirth. The herbs ... -
Effects of graded doses of the pesticide heptachlor on body weight, mating success, oestrous cycle, gestation length and litter size in laboratory rats
(Pergamon, 1995-05-01)Adult female Sprague-Dawley rats were injected with 5 or 20 mg/kg body weight heptachlor solution every other day for up to 18 days. They were weighed every day and the stage of oestrus determined by vaginal smears. ... -
In vivo and in vitro effects of graded doses of the pesticide heptachlor on female sex steroid hormone production in rats
(Pergamon, 1995-05-01)Adult female Sprague-Dawley rats were injected with corn oil or 5 mg, 20 mg, 25 mg or 30 mg per kg body weight of heptachlor solution every other day for up to 18 days. The rats were killed at the end of the experimental ... -
Changes in the concentrations of testosterone, luteinising hormone and progesterone associated with administration of embelin
(Elsevier, 1991-10-01)The mode of action of embelin, a naturally occurring plant benzoquinone with male fertility regulating potential, was investigated. Sexually mature white New Zealand male rabbits were injected intra-muscularly with ...