School of Medicine: Recent submissions
Now showing items 541-560 of 567
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Interaction of benzoquinones with mitochondria interferes with oxidative phosphorylation characteristics
(No longer published by Elsevier, 1990-08-06)Studies with four benzoquinones, viz. juglone, embelin, maesaquinone and maesanin, on rat liver mitochondria oxidative phosphorylation have been carried out. Three of the benzoquinones are uncouplers in the order ... -
Medicinal plants used in the treatment of fungal and bacterial infections in and around Queen Elizabeth Biosphere Reserve, western Uganda
(Blackwell Publishing Ltd, 2008-06-01)In Uganda, bacterial and fungal infections are prevalent especially, the sexually transmitted diseases including HIV/AIDS. Because of low socio-economic empowerment, traditional beliefs and cultural barriers, the ... -
Reduced immune complex binding capacity and increased complement susceptibility of red cells from children with severe malaria-associated anemia
(The Feinstein Institute for Medical Research, 2008-03)Plasmodium falciparum malaria causes 1–2 million deaths per year. Most deaths occur as a result of complications such as severe anemia and cerebral malaria (CM)(coma). Red cells of children with severe malaria-associated ... -
Reflections on the first pan‐african conference on biochemistry and molecular biology
(Headington Hill Hall, 1997-07-01)After a couple of years of consultations with leading biochemists/molecular biologists in Africa and from abroad (playing advisory roles), the First Pan-African Conference on Biochemistry and Molecular Biology was ... -
Molecular approaches to parasitology Edited by John C Boothroyd and Richard Komuniecki, pp 560. Wiley‐Liss, New York, 1995.£ 49.95 ISBN 0‐471‐10342‐X (Ha...
Of the currently known 12.5 million organic compounds, about half of them contain heterocyclic systems. Biochemists, of course, know very well the importance of such compounds in all life processes, not to mention the ... -
Progesterone, estradiol and their respective receptors in leiomyoma and adjacent normal myometria of black Kenyan women
(University of Nairobi, 2018) -
Medical terminology: A programmed text 7th edition: By GL Smith, PE Davis and JT Dennerll. P 500. Delmar, New York. 1995.£ 28.50 ISBN 0‐8273‐6304‐4
(Headington Hill Hall, 1996-01-01)NMR has become one of the most powerful biophysical techniques with a wide range of applications, and yet many regard it as being difficult to understand. This attitude is not confined to undergraduates, although they ... -
Molecular Approaches to Parasitology
(1996) -
Reproductive toxicology: Edited by Raphael J Witorsch. pp 335. Raven Press, New York. 1995 ISBN 0‐7818‐0225‐9
(Headington Hill Hall, 1995-07-01)This volume incorporates material on stilbenes, bibenzyls, phenanthrene, their 9, 10- derivatives, and related plant products (similar in biosynthesis to fiavonoids), all derived from cinnamic acid and malonyl-CoA. The ... -
Experimental kwashiokor and obesity
(1991)Obesity and kwashiorkor syndrome were experimentally simulated in sprague dawley weaning rats to investigate the changes in energy metabolism and relative organ body weight ratios during over nutrition and under ... -
Interaction of benzoquinones with mitochondria interferes with oxidative phosphorylation characteristics
(University of Nairobi, 1990)Studies with four benzoquinones, viz. juglone, embelin, maesaquinone and maesanin, on rat liver mitochondria oxidative phosphorylation have been carried out. Three of the benzoquinones are uncouplers in the order ... -
Pitting of malaria parasites and spherocyte formation
(Pub Med Central, 2006-07-31)BACKGROUND: A high prevalence of spherocytes was detected in blood smears of children enrolled in a case control study conducted in the malaria holoendemic Lake Victoria basin. It was speculated that the spherocytes ... -
Impact of RTS,S/AS02(A) and RTS,S/AS01(B) on genotypes of P. falciparum in adults participating in a malaria vaccine clinical trial.
(Pub Med Central, 2009-11-17)OBJECTIVE: RTS,S, a candidate vaccine for malaria, is a recombinant protein expressed in yeast containing part of the circumsporozoite protein (CSP) sequence of 3D7 strain of Plasmodium falciparum linked to the hepatitis ... -
Outpatient upper respiratory tract viral infections in children with malaria symptoms in Western Kenya.
(Pub Med Central, 2010-11)A cross-sectional study was performed in children 5 through 10 years of age presenting to outpatient clinics in Nyanza Province, Kenya, in which nasal swab and blood specimens were collected during the high malaria ... -
Malaria prevalence defined by microscopy, antigen detection, DNA amplification and total nucleic acid amplification in a malaria-endemic region during the peak malaria transmission season
(Pub Med Central, 2011-07)OBJECTIVES: To determine the malaria prevalence by microscopy, antigen detection and nucleic acid detection in a defined subpopulation in a Plasmodium falciparum-endemic region during the peak transmission season. ME ... -
Functional haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children.
(Pub Med Central, 2012-02)Development of protective immunity against Plasmodium falciparum is partially mediated through binding of malaria-specific IgG to Fc gamma (γ) receptors. Variation in human FcγRIIA-H/R-131 and FcγRIIIB-NA1/NA2 affect ... -
Polymorphic variability in the 3' untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falciparum malaria
(Pub Med Central, 2011-08)BACKGROUND: Plasmodium falciparum malaria remains a leading cause of morbidity and mortality among African children. Innate immunity provides the first line of defence against P. falciparum infections, particularly in young ... -
Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality
(Pub Med Central, 2011-12)Severe malarial anemia (SMA) is a leading cause of morbidity and mortality in children residing in regions where Plasmodium falciparum transmission is holoendemic. Although largely unexplored in children with SMA, ...